The protein entries are assigned to XXX homologous subfamilies (homology groups) which are grouped into XXX families. Entries were assigned to homology subfamilies according to sequence similarity by performing multisequence alignments and phylogenetic analyses.
For each homology subfamily, pre-calculated multiple alignments and phylogenetic trees are supplied here (lien a mettre quand j'aurais fait). Some proteins within the database could not be classified by sequence similarity and were grouped in the 'OTHER' group. They will be reassigned during a database update in case of the classification procedure evolves. A table permits browsing of the database by homology group ('List').
Protein names contain links to their respective GeneCards entry. A browsable tree which allows the retrieval of entries by homology is also available ('Hierarchic tree'), at present manually constructed based on sequence and phylogenetic analyses. Clicking on names allows selection of homology subfamilies (corresponding to the well-known family members) while clicking on branches allows selection of homologous families regrouping several family members (Bcl-2 family member'-LIKE').